Testosterone replacement affects disease risk

Testosterone replacement therapy and the risk of prostate cancer.

Understanding the role of testosterone replacement therapy (TRT) in the development and progression of prostate cancer is an important concept in treating patients with symptoms of hypogonadism. This article revealed a small number of mostly retrospective, observational studies describing the use of TRT in the general population, in men with prostatic intraepithelial neoplasia (PIN), in men wit...

Prostate Cancer and Testosterone Replacement Therapy--What is the Risk?

www.trendsinmenshealth.com TRENDS IN UROLOGY & MEN’S HEALTH JANUARY/FEBRUARY 2017 The last decade has seen a rise in testosterone replacement therapy (TRT) internationally.1 Controversy continues, however, on the impact of TRT and its effect on the prostate. While the effects of TRT on benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) are as yet unsettled, the role of T...

Corrigendum: Testosterone Replacement Therapy and Cardiovascular Risk: A Review

Recent reports in the scientific and lay press have suggested that testosterone (T) replacement therapy (TRT) is likely to increase cardiovascular (CV) risk. In a final report released in 2015, the Food and Drug Administration (FDA) cautioned that prescribing T products is approved only for men who have low T levels due to primary or secondary hypogonadism resulting from problems within the tes...

testosterone replacement helps

Which testosterone replacement therapy?

Three different forms of testosterone (T) replacement therapy were compared; they were the intramuscular injection of mixed testosterone esters 250 mg; the subcutaneous implantation of 6 X 100 mg pellets of fused testosterone; and the oral administration of testosterone undecanoate (TU) 80 mg twice daily. Six hypogonadal males were treated with oral TU for an eight week period, during which tim...